The Composition of Naja naja Venom Samples from Three Districts of West Bengal, India

Mukherjee, A.K ; Maity, C.R (1998) The Composition of Naja naja Venom Samples from Three Districts of West Bengal, India Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 119 (2). pp. 621-627. ISSN 10956433

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Official URL: http://doi.org/10.1016/s1095-6433(97)00475-3

Related URL: http://dx.doi.org/10.1016/s1095-6433(97)00475-3

Abstract

The variation in the composition of Naja naja venoms from three neighbouring districts of West Bengal, eastern India and the corresponding differences in the severity of pathogenesis due to venom composition variation are reported. These venom samples differ with respect to chromatographic elution profile and enzyme activity associated with each fraction. Presence of higher quantities of basic phospholipase and plasma protein hydrolase in the venom samples of Burdwan and Purulia make them more toxic than Midnapur venom sample. A polyvalent antivenom manufactured in western India was hardly effective in neutralizing the pathobiological manifestation of the venom samples from eastern India.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science Inc.
Keywords:Naja naja, cobra venom, protease, phospholipase A2, myotoxicity, edema-induction, antivenom, venom-neutralization
ID Code:126916
Deposited On:13 Oct 2022 08:50
Last Modified:13 Oct 2022 08:50

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