Facially-selective thymine–thymine photodimerization in TTT triads

Neelakandan, Prakash P. ; Pan, Zhengzheng ; Hariharan, Mahesh ; Lewis, Frederick D. (2012) Facially-selective thymine–thymine photodimerization in TTT triads Photochemical & Photobiological Sciences, 11 (6). p. 889. ISSN 1474-905X

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Official URL: http://doi.org/10.1039/c2pp25089f

Related URL: http://dx.doi.org/10.1039/c2pp25089f

Abstract

Irradiation of alkane-linked DNA hairpins possessing TTT steps with flanking purine bases yields products identified as the cis–syn (2 + 2) dimers formed between the central thymine and its 3′- and 5′-neighbors. Selective formation of the 3′-dimer is attributed to ground state conformational effects and electron transfer quenching by purine bases.

Item Type:Article
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ID Code:126785
Deposited On:29 Sep 2022 11:02
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