Conformational Control of Thymine Photodimerization in Single-Strand and Duplex DNA Containing Locked Nucleic Acid TT Steps

Hariharan, Mahesh ; McCullagh, Martin ; Schatz, George C. ; Lewis, Frederick D. (2010) Conformational Control of Thymine Photodimerization in Single-Strand and Duplex DNA Containing Locked Nucleic Acid TT Steps Journal of the American Chemical Society, 132 (44). p. 15831. ISSN 0002-7863

Full text not available from this repository.

Official URL: http://doi.org/10.1021/ja108528q

Related URL: http://dx.doi.org/10.1021/ja108528q

Abstract

The results of an integrated experimental and theoretical study of thymine-thymine photodimerization in short single-strand and duplex DNA structures possessing a single locked nucleic acid TT step are reported. Control of ground-state conformation by the locked nucleic acids results in a marked increase in both the quantum yield and the selectivity of photoproduct formation.

Item Type:Article
Source:Copyright of this article belongs to ResearchGate GmbH.
ID Code:126777
Deposited On:29 Sep 2022 11:01
Last Modified:29 Sep 2022 11:01

Repository Staff Only: item control page