Palladium-Catalyzed Pyridine-Directed Regioselective Oxidative C-H Acylation of Carbazoles by Using Aldehydes as the Acyl Source

Maiti, Subhadip ; Burgula, Laxminarayana ; Chakraborti, Gargi ; Dash, Jyotirmayee (2016) Palladium-Catalyzed Pyridine-Directed Regioselective Oxidative C-H Acylation of Carbazoles by Using Aldehydes as the Acyl Source European Journal of Organic Chemistry, 2017 (2). pp. 332-340. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201601322

Related URL: http://dx.doi.org/10.1002/ejoc.201601322

Abstract

We have developed a regioselective pyridyl-directed C–H acylation reaction of carbazoles that employs aldehydes as the acyl source and provides C-1 and C-8 diacylated products in good to high yields. Dihalogenated carbazoles, however, afford 1-acylated products. A key feature of this strategy includes the use of the easily removable pyridyl-directing group.

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ID Code:126628
Deposited On:17 Oct 2022 05:45
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