Kumar, Y. Pavan ; Das, Rabindra Nath ; Kumar, Sonu ; Schütte, Ole Mathis ; Steinem, Claudia ; Dash, Jyotirmayee (2014) Triazole-Tailored Guanosine Dinucleosides as Biomimetic Ion Channels to Modulate Transmembrane Potential Chemistry - A European Journal, 20 (11). pp. 3023-3028. ISSN 0947-6539
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Official URL: http://doi.org/10.1002/chem.201304530
Related URL: http://dx.doi.org/10.1002/chem.201304530
Abstract
Coming through: A “click” ion-channel platform was established by employing a clickable guanosine azide or alkyne with covalent spacers. The guanosine derivatives modulated the traffic of ions across the phospholipid bilayer. FRET studies of the dansyl fluorophore with the membrane-binding fluorophore Nile red revealed that the dansyl fluorophore is deeply embedded in the phospholipid bilayer.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| ID Code: | 126578 |
| Deposited On: | 17 Oct 2022 05:48 |
| Last Modified: | 17 Oct 2022 05:48 |
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