Dash, Jyotirmayee ; Lechel, Tilman ; Reissig, Hans-Ulrich (2007) Scope of a Novel Three-Component Synthesis of Highly Functionalized Pyridines Organic Letters, 9 (26). pp. 5541-5544. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/ol702468s
Related URL: http://dx.doi.org/10.1021/ol702468s
Abstract
A mechanistically unique three-component synthesis provides a variety of functionalized pyridine derivatives in fair to excellent yields. The scope of this reaction was studied with respect to the alkoxyallene, the nitrile, and the carboxylic acid. Due to the 4-hydroxy group, these pyridine derivatives are suitable precursors for subsequent palladium-catalyzed reactions. Suzuki couplings of the corresponding pyridyl nonaflates lead to a variety of pyridine and bipyridine derivatives.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 126514 |
| Deposited On: | 17 Oct 2022 05:53 |
| Last Modified: | 17 Oct 2022 05:53 |
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