Maternal Vitamin B12 Status and Risk of Cleft Lip and Cleft Palate Birth Defects in Tamil Nadu State, India

Munger, Ronald G. ; Kuppuswamy, Rajarajeswari ; Murthy, Jyotsna ; Balakrishnan, Kalpana ; Thangavel, Gurusamy ; Sambandam, Sankar ; Kurpad, Anura V. ; Molloy, Anne M. ; Ueland, Per M. ; Mossey, Peter A. (2021) Maternal Vitamin B12 Status and Risk of Cleft Lip and Cleft Palate Birth Defects in Tamil Nadu State, India The Cleft Palate-Craniofacial Journal, 58 (5). pp. 567-576. ISSN 1055-6656

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Official URL: http://doi.org/10.1177/1055665621998394

Related URL: http://dx.doi.org/10.1177/1055665621998394

Abstract

The causal role of maternal nutrition in orofacial clefts is uncertain. We tested hypotheses that low maternal vitamin B12 and low folate status are each associated with an increased risk of isolated cleft lip, with or without cleft palate, (CL+P) in a case-control study in Tamil Nadu state, India.

Item Type:Article
Source:Copyright of this article belongs to ResearchGate GmbH
Keywords:Orofacial clefts, Cleft lip, Cleft palate, Congenital anomalies, Birth defects, Pregnancy, Maternal nutrition, Vitamin B12, Cobalamin, Methylmalonic acid, Folate, Homocysteine, India, Tamil Nadu
ID Code:126061
Deposited On:13 Oct 2022 05:37
Last Modified:13 Oct 2022 05:37

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