Measuring vitamin B-12 bioavailability with [13C]-cyanocobalamin in humans

Devi, Sarita ; Pasanna, Roshni M ; Shamshuddin, Zeeshan ; Bhat, Kishor ; Sivadas, Ambily ; Mandal, Amit K ; Kurpad, Anura V (2020) Measuring vitamin B-12 bioavailability with [13C]-cyanocobalamin in humans The American Journal of Clinical Nutrition, 112 (6). pp. 1504-1515. ISSN 0002-9165

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Official URL: http://doi.org/10.1093/ajcn/nqaa221

Related URL: http://dx.doi.org/10.1093/ajcn/nqaa221

Abstract

Vitamin B-12 deficiency is widespread in many parts of the world, affecting all age groups and increasing with age. It is primarily due to a low intake of animal source foods or malabsorption. The measurement of bioavailability of vitamin B-12 is etiologically important in deficiency but is limited due to the use of radioactive isotopes like [57Co]- or [14C]-cyanocobalamin.

Item Type:Article
Source:Copyright of this article belongs to The Author(s) on behalf of the American Society for Nutrition 2020
Keywords:bioavailability; biosynthesis; cyanocobalamin; human; mass spectrometry; methylcobalamin; pharmacokinetics; stable isotope; vitamin B-12.
ID Code:125977
Deposited On:13 Oct 2022 04:23
Last Modified:13 Oct 2022 04:23

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