Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum

Sapkal, Gajanan N. ; Yadav, Pragya D. ; Ella, Raches ; Deshpande, Gururaj R. ; Sahay, Rima R. ; Gupta, Nivedita ; Mohan, V Krishna ; Abraham, Priya ; Panda, Samiran ; Bhargava, Balram (2021) Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum bioRxiv .

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Official URL: http://doi.org/10.1101/2021.01.26.426986

Related URL: http://dx.doi.org/10.1101/2021.01.26.426986

Abstract

We performed the plaque reduction neutralization test (PRNT50) using sera collected from the recipients of BBV152/COVAXIN™ against hCoV-19/India/20203522 (UK-variant) and hCoV27 19/India/2020Q111 (heterologous strain). A comparable neutralization activity of the vaccinated individuals sera showed against UK-variant and the heterologous strain with similar efficiency, dispel the uncertainty of possible neutralization escape.

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Deposited On:07 Feb 2022 10:53
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