Handore, Kishor L. ; Reddy, D. Srinivasa (2013) A Diverted Total Syntheses of Potent Cell Adhesion Inhibitor Peribysin E Analogues Organic Letters, 15 (8). pp. 1894-1897. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/ol400555m
Related URL: http://dx.doi.org/10.1021/ol400555m
Abstract
Preliminary results from a program aimed at the creation of a focused library of analogues around the natural product peribysin E, a potent biologically active and structurally fascinating molecule, are reported. The total synthesis of (±)-peribysin E was accomplished using a short route. Eight new analogues of the natural compound have been accomplished by means of “diverted total synthesis” in less than 10 steps. The present effort highlights protecting-group-free total syntheses and the shortest route to access these functionally embellished hydrindanes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society |
| ID Code: | 121964 |
| Deposited On: | 23 Jul 2021 10:40 |
| Last Modified: | 23 Jul 2021 10:40 |
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