Handore, Kishor L. ; Reddy, D. Srinivasa (2014) Total Synthesis of (±)-Nardoaristolone B and Its Analogues Organic Letters, 16 (16). pp. 4252-4255. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/ol501949r
Related URL: http://dx.doi.org/10.1021/ol501949r
Abstract
The first total synthesis of nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes, has been accomplished. Stereoselective synthesis of its novel analogues inlcuding exo-cyclopropyl ring fusion is also part of this disclosure. In addition, an alternate and more efficient one-step method to make a 3/5/6 tricyclic ring system using the Robinson annulation method has been developed toward the generation of a library of compounds around this skeleton.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society |
| ID Code: | 121953 |
| Deposited On: | 23 Jul 2021 09:57 |
| Last Modified: | 23 Jul 2021 09:57 |
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