First synthesis of nitrosporeusines, alkaloids with multiple biological activities

Philkhana, Satish Chandra ; Jachak, Gorakhnath R. ; Gunjal, Vidya B. ; Dhage, Nagsen M. ; Bansode, Ajay H. ; Reddy, D. Srinivasa (2015) First synthesis of nitrosporeusines, alkaloids with multiple biological activities Tetrahedron Letters, 56 (10). pp. 1252-1254. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2015.01.143

Related URL: http://dx.doi.org/10.1016/j.tetlet.2015.01.143

Abstract

Synthesis of nitrosporeusines A and B, thioester-bearing alkaloids from the Arctic Streptomyces nitrosporeus with exceptional biological activity is disclosed for the first time. In addition, we have prepared another biologically important natural product, maleimycin, in optically pure form using a gram-scale enzymatic resolution method.

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ID Code:121950
Deposited On:23 Jul 2021 09:48
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