Total Synthesis and Structural Revision of Mycalol, an Anticancer Natural Product from the Marine Source

Seetharamsingh, B. ; Rajamohanan, P. R. ; Reddy, D. Srinivasa (2015) Total Synthesis and Structural Revision of Mycalol, an Anticancer Natural Product from the Marine Source Organic Letters, 17 (7). pp. 1652-1655. ISSN 1523-7060

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Official URL: http://doi.org/10.1021/acs.orglett.5b00345

Related URL: http://dx.doi.org/10.1021/acs.orglett.5b00345

Abstract

The total synthesis of an anticancer (anaplastic thyroid) natural lipid mycalol has been accomplished for the first time. Synthesis of originally proposed structure necessitated the revision of structure in which the position of acetate group moved from C20 to C19 and a change in stereochemistry of the glycerol unit.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:121949
Deposited On:23 Jul 2021 09:44
Last Modified:23 Jul 2021 09:44

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