Multi-gram scale synthesis of hunanamycin A, an antibiotic natural product from the marine source

Shingare, Rahul D. ; Farhana, Sa ada ; Reddy, D. Srinivasa (2016) Multi-gram scale synthesis of hunanamycin A, an antibiotic natural product from the marine source Tetrahedron Letters, 57 (32). pp. 3662-3663. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2016.07.003

Related URL: http://dx.doi.org/10.1016/j.tetlet.2016.07.003

Abstract

A simple, practical, and biomimetic approach to access antibiotic natural product hunanamycin A starting from readily available inexpensive material Riboflavin is disclosed here. The present synthesis consists of three operationally simple, protecting group free steps and it is far superior when compared with the previous route. Using this route one can make multi-gram quantities of the natural product which will help in further biological assays, in particular exploring the potential of treating food infections.

Item Type:Article
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Deposited On:23 Jul 2021 08:52
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