Ruthenium-Catalyzed Intramolecular Hydroarylation of Arenes with Olefins in Water

Mukherjee, Kallol ; Ramesh, E. ; Ghosh, Koushik ; Sahoo, Akhila K. (2018) Ruthenium-Catalyzed Intramolecular Hydroarylation of Arenes with Olefins in Water Asian Journal of Organic Chemistry, 7 (7). pp. 1380-1384. ISSN 2193-5807

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Official URL: http://doi.org/10.1002/ajoc.201800241

Related URL: http://dx.doi.org/10.1002/ajoc.201800241

Abstract

A Ru-catalyzed intramolecular hydroarylation of arenes in an aqueous medium is presented herein. With the aid of methyl phenyl sulfoximine or an amide directing group, this atom-efficient hydroarylation of arenes ensued dihydrobenzofuran derivatives. Sequential double hydroarylation of arene motifs resulted in highly peripheral-decorated heterocycles. Deuterium labeling studies and control experiments offer valuable information in understanding the reactivity and the mechanistic data.

Item Type:Article
Source:Copyright of this article belongs to John Wiley & Sons, Inc.
ID Code:121868
Deposited On:22 Jul 2021 18:30
Last Modified:22 Jul 2021 18:30

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