Bhatti, H. S. ; Bhushnurmath, S. ; Mahajan, R. C. ; Ganguly, N. K. ; Sehgal, R. (1992) An experimental model of ameboma in guinea pig Experimental Parasitology, 74 (3). pp. 283-289. ISSN 0014-4894
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001448...
Related URL: http://dx.doi.org/10.1016/0014-4894(92)90151-Y
Abstract
Among the wide variety of clinicopathological manifestations of intestinal amebiasis, amebomas occur rarely and their pathogenesis is not well understood. When cholesterol-fed, 2- to 4-week-old guinea pigs were infected intracecally with a virulent, monoaxenic strain of Entamoeba histolytica, gross and histologically characteristic amebomas developed in 85% of the animals by the 3rd day, in 94% by the 9th day, and in 96% by the 12th day postinfection, by which time most of them had died. Amebomas were confirmed by histopathology. Thus, a model of consistent production of amebomas was documented.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Guinea Pig; Experimental Model; Ameboma; Entamoeba Histolytica |
| ID Code: | 12169 |
| Deposited On: | 10 Nov 2010 04:14 |
| Last Modified: | 31 May 2011 10:39 |
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