Cinchonine catalyzed diastereo- and enantioselective Michael addition of α-lithiated phosphonates to nitroalkenes

Rai, Vishal ; Mobin, Shaikh M. ; Namboothiri, Irishi N.N. (2007) Cinchonine catalyzed diastereo- and enantioselective Michael addition of α-lithiated phosphonates to nitroalkenes Tetrahedron: Asymmetry, 18 (22). pp. 2719-2726. ISSN 0957-4166

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Official URL: http://doi.org/10.1016/j.tetasy.2007.11.001

Related URL: http://dx.doi.org/10.1016/j.tetasy.2007.11.001

Abstract

Conjugate addition of α-lithiated benzyl- and alkylphosphonates to a variety of aromatic and heteroaromatic nitroalkenes in the presence of 50 mol % of cinchonine-Li catalyst system proceeded in high yields, diastereo- and enantioselectivities in most cases.

Item Type:Article
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ID Code:121584
Deposited On:19 Jul 2021 10:45
Last Modified:19 Jul 2021 10:45

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