Gupta, R. ; Verma, I. ; Sharma, S. ; Ganguly, N. K. (2004) Prevention of tissue injury in an ascending mouse model of chronic pyelonephritis-role of free radical scavengers Comparative Immunology, Microbiology & Infectious Diseases, 27 (4). pp. 225-234. ISSN 0147-9571
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S01479...
Related URL: http://dx.doi.org/10.1016/S0147-9571(03)00011-0
Abstract
The role of free radical scavengers in preventing the tissue injury using a non obstructive, ascending mouse model for chronic pyelonephritis was assessed. The parameters taken into consideration are Luminol Dependent Chemiluminescence (LDCL), histopathology and some biochemical investigations. We have observed that both catalase and Dimethyl-Sulfoxide (DMSO, free radical scavengers) were able to prevent the free radical mediated tissue injury and ultimate renal scarring, irrespective of the bacterial strain studied.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 12152 |
| Deposited On: | 10 Nov 2010 04:08 |
| Last Modified: | 31 May 2011 10:19 |
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