Hepatitis E virus transmission to a volunteer

Chauhan, A. ; Dilawari, J. B. ; Chawla, Y. K. ; Jameel, S. ; Kaur, U. ; Ganguly, N. K. (1993) Hepatitis E virus transmission to a volunteer Lancet, 341 (8838). pp. 149-150. ISSN 0099-5355

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/014067...

Related URL: http://dx.doi.org/10.1016/0140-6736(93)90008-5


Hepatitis E virus (HEV) causes an enteric non-A, non-B hepatitis. The disease occurs in epidemic settings and sporadically, and viral transmission is thought to be faecal-oral. We present here a single volunteer study of HEV transmission followed by disease. Clinical and biochemical features of the infection correlated with H EV detection in the stools and sera by reverse transcription/polymerase chain amplification. IgG antibody has persisted for 2 years. The presence of HEV in serum before clinical signs appeared suggests that in endemic areas sporadic transmission of HEV may also occur parenterally.

Item Type:Article
Source:Copyright of this article belongs to Lancet.
ID Code:12141
Deposited On:10 Nov 2010 04:17
Last Modified:11 Jul 2012 10:28

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