α-Functionalization of Nitroalkenes and Its Applications in Organic Synthesis

Namboothiri, Irishi ; Nair, Divya ; Kumar, Tarun (2016) α-Functionalization of Nitroalkenes and Its Applications in Organic Synthesis Synlett, 27 (17). pp. 2425-2442. ISSN 0936-5214

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Official URL: http://doi.org/10.1055/s-0036-1588587

Related URL: http://dx.doi.org/10.1055/s-0036-1588587

Abstract

The applications of Morita–Baylis–Hillman (MBH) and Rauhut–Currier (RC) adducts of nitroalkenes in the synthesis of various carbo- and heterocycles are summarized in this review. In recent years, the MBH adducts and their derivatives such as acetates and bromides have served as efficient synthons for the synthesis of bioactive compounds including natural products. The close proximity of various functional groups makes the MBH and RC adducts extremely valuable substrates in multicomponent and cascade reactions, including annulations, organocatalysis, and kinetic resolution, to name a few.

Item Type:Article
Source:Copyright of this article belongs to Georg Thieme Verlag.
ID Code:121326
Deposited On:14 Jul 2021 10:04
Last Modified:14 Jul 2021 10:04

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