The complexity of mitochondrial tRNA import

Bhattacharyya, Suvendra Nath ; Adhya, Samit (2004) The complexity of mitochondrial tRNA import RNA Biology, 1 (2). pp. 84-88. ISSN 1547-6286

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Import of nucleus-encoded, cytoplasmic tRNAs into mitochondria to compensate evolutionary loss of the corresponding mitochondrial genes has been documented in a large number of species. Although the phenomenon has been known for more than 25 years, it was only recently that the mechanism of tRNA import started receiving the sustained attention of workers investigating yeast, protozoal and higher plant systems. The purpose of this review is to summarize recent developments that shed new light on the selectivity of the process, the identity of the import apparatus and the nature of the bioenergetic transactions leading to tRNA translocation, and to build a working model of the import complex suggested by these observations.

Item Type:Article
Source:Copyright of this article belongs to Landes Bioscience.
ID Code:12112
Deposited On:10 Nov 2010 04:29
Last Modified:16 May 2016 21:31

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