A New One-Pot Synthetic Approach to the Highly Functionalized (Z)-2-(Buta-1,3-dienyl)phenols and 2-Methyl-2H-chromenes: Use of Amine, Ruthenium and Base-Catalysis

Ramachary, Dhevalapally B. ; Narayana, Vidadala V. ; Ramakumar, Kinthada (2008) A New One-Pot Synthetic Approach to the Highly Functionalized (Z)-2-(Buta-1,3-dienyl)phenols and 2-Methyl-2H-chromenes: Use of Amine, Ruthenium and Base-Catalysis European Journal of Organic Chemistry, 2008 (23). pp. 3907-3911. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.200800472

Related URL: http://dx.doi.org/10.1002/ejoc.200800472

Abstract

A novel and practical one-pot multi-catalysis process for the synthesis of highly substituted benzo[b]oxepines 5, (Z)-2-(buta-1,3-dienyl)phenols 6 and 2-methyl-2H-chromenes 7 from simple starting materialsis described. (Z)-2-(buta-1,3-dienyl)phenols 6 are obtained via base-induced ring opening of highly functionalized benzo[b]oxepines 5.

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