Sequential Combination of Ruthenium-, Base-, and Gold-Catalysis - A New Approach to the Synthesis of Medicinally Important Heterocycles

Ramachary, Dhevalapally B. ; Narayana, Vidadala V. (2011) Sequential Combination of Ruthenium-, Base-, and Gold-Catalysis - A New Approach to the Synthesis of Medicinally Important Heterocycles European Journal of Organic Chemistry, 2011 (19). pp. 3514-3522. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201100040

Related URL: http://dx.doi.org/10.1002/ejoc.201100040

Abstract

A novel process for the synthesis of highly substituted, medicinally important heterocycles was achieved through the sequential combination of ring-closing methathesis, base-induced ring opening, hydroamination, and Diels–Alder reaction of functionalized allyl-(2-allylphenyl)amines in the presence of a catalytic amount of [Ru], base, and [Au] (see scheme).

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
ID Code:120760
Deposited On:05 Jul 2021 05:15
Last Modified:05 Jul 2021 05:15

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