Discovery of 2-aminobuta-1,3-enynes in asymmetric organocascade catalysis: construction of drug-like spirocyclic cyclohexanes having five to six contiguous stereocenters

Ramachary, Dhevalapally B. ; Venkaiah, Chintalapudi ; Murali Krishna, Patoju (2012) Discovery of 2-aminobuta-1,3-enynes in asymmetric organocascade catalysis: construction of drug-like spirocyclic cyclohexanes having five to six contiguous stereocenters Chemical Communications, 48 (16). p. 2252. ISSN 1359-7345

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Official URL: http://doi.org/10.1039/C2CC17219D

Related URL: http://dx.doi.org/10.1039/C2CC17219D

Abstract

We present herein for the first time the asymmetric synthesis of drug-like spiranes through reflexive-Michael reaction by using 2-aminobuta-1,3-enyne catalysis under mild conditions.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:120677
Deposited On:03 Jul 2021 08:05
Last Modified:03 Jul 2021 08:05

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