A Brønsted Acid-Primary Amine as a Synergistic Catalyst for Stereoselective Asymmetric Diels-Alder Reactions

Ramachary, Dhevalapally B. ; Reddy, P. Sreekanth ; Shruthi, Kodambahalli S. ; Madhavachary, R. ; Reddy, P. V. Govardhana (2016) A Brønsted Acid-Primary Amine as a Synergistic Catalyst for Stereoselective Asymmetric Diels-Alder Reactions European Journal of Organic Chemistry, 2016 (31). pp. 5220-5226. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.201601011

Related URL: http://dx.doi.org/10.1002/ejoc.201601011

Abstract

An effective Barbas [4+2]-cycloaddition is disclosed to access druglike six-membered spirooxindoles from simple aliphatic substrates in good yields with excellent enantioselectivities through synergistic amine/acid catalysis. DCE = 1,2-dichloroethane.

Item Type:Article
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ID Code:120659
Deposited On:03 Jul 2021 06:58
Last Modified:03 Jul 2021 06:58

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