Organocatalytic Asymmetric Formal [3+3]‐Cycloaddition to Access 2,3‐Diazaspiro[4.5]deca‐3,6‐dien‐1‐ones

Krishna, A. Vamshi ; Reddy, G. Surendra ; Gorachand, B. ; Ramachary, Dhevalapally B. (2020) Organocatalytic Asymmetric Formal [3+3]‐Cycloaddition to Access 2,3‐Diazaspiro[4.5]deca‐3,6‐dien‐1‐ones European Journal of Organic Chemistry, 2020 (42). pp. 6623-6628. ISSN 1434-193X

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Official URL: http://doi.org/10.1002/ejoc.202001175

Related URL: http://dx.doi.org/10.1002/ejoc.202001175

Abstract

Single structure out of many domino reactions! Double sequence of isoaromatization and dearomatization driven the domino Michael/aldol or formal [3+3]-cycloaddition as an efficient tool for the construction of chiral drug-like 2,3-diazaspiro[4.5]deca-3,6-dien-1-ones having spirocyclic vicinal quaternary carbon centers.

Item Type:Article
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ID Code:120632
Deposited On:02 Jul 2021 13:34
Last Modified:02 Jul 2021 13:34

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