Application of cyclic-1,3-diketones in domino and multicomponent reactions: facile route to highly functionalized chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones under solvent-free conditions

Kumar, Ram ; Raghuvanshi, Keshav ; Verma, Rajiv K. ; Singh, Maya S. (2010) Application of cyclic-1,3-diketones in domino and multicomponent reactions: facile route to highly functionalized chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones under solvent-free conditions Tetrahedron Letters, 51 (45). pp. 5933-5936. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2010.09.017

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.09.017

Abstract

A facile and efficient protocol for the synthesis of chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones has been developed by one-pot three-component cyclocondensation of aldehydes, cyclic-1,3-diketones and 1,3-dimethylbarbituric acid in the presence of InCl 3 or P 2 O 5 under solvent-free conditions.

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