Muthyala, Ramaiah ; Nagaraju, Anugula ; Ramulu, B. Janaki ; Shukla, Gaurav ; Srivastava, Abhijeet ; Verma, Girijesh Kumar ; Singh, Maya Shankar (2015) Solvent-free one-pot efficient and highly regioselective access to functionalized thiazolopyridones from α-enolic dithioesters Arkivoc, 2016 (2). pp. 42-52. ISSN 1551-7012
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Official URL: http://doi.org/10.3998/ark.5550190.p009.179
Related URL: http://dx.doi.org/10.3998/ark.5550190.p009.179
Abstract
An operationally simple, highly convergent and straightforward synthesis of diverse thiazolopyridones has been achieved via three-component domino coupling (3CDC) of α-enolic dithioesters, cysteamine and dialkyl acetylenedicarboxylates under solvent-free conditions. The approach is carbon-economic and relies on sequential cyclic N,S-acetal formation/Michael addition/N-cyclization cascade forming consecutive CC , C-N and C-S bonds in one-pot.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Arkat USA Inc. |
| ID Code: | 119611 |
| Deposited On: | 15 Jun 2021 06:19 |
| Last Modified: | 15 Jun 2021 06:19 |
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