TSH response to TRH and ECT

Hofmann, P. ; Gangadhar, B.N. ; Probst, Ch. ; Koinig, G. ; Hatzinger, R. (1994) TSH response to TRH and ECT Journal of Affective Disorders, 32 (2). pp. 127-131. ISSN 0165-0327

Full text not available from this repository.

Official URL: http://doi.org/10.1016/0165-0327(94)90070-1

Related URL: http://dx.doi.org/10.1016/0165-0327(94)90070-1


In 31 female patients diagnosed according to DSM-III-R criteria as suffering from ‘functional’ psychosis (e.g., major depression, schizophrenia, mania) TRH tests were administered before, during and after a course of electroconvulsive therapy (ECT) to investigate the effects of ECT on HPT (hypothalamic-pituitary-thyroid) axis as well as the predictive value of TSH response to TRH on treatment outcome. In 20 patients all three TRH tests were available; no significant changes in the mean TSH response were found over the course of ECT; however, a change towards blunted TSH response at the end of treatment was observed. The initial TSH response did not predict the treatment outcome.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Electroconvulsive Therapy; Thyrotropin-releasing Hormone; Major Depression; Schizophrenia; Hypothalamic-Pituitary-Thyroid-Axis.
ID Code:119439
Deposited On:13 Jun 2021 12:02
Last Modified:13 Jun 2021 12:02

Repository Staff Only: item control page