‘Normal’ P300 amplitude predicts rapid response to ECT in melancholia

Ancy, J. ; Gangadhar, B.N. ; Janakiramaiah, N. (1996) ‘Normal’ P300 amplitude predicts rapid response to ECT in melancholia Journal of Affective Disorders, 41 (3). pp. 211-215. ISSN 0165-0327

Full text not available from this repository.

Official URL: http://doi.org/10.1016/S0165-0327(96)00090-0

Related URL: http://dx.doi.org/10.1016/S0165-0327(96)00090-0


Consenting melancholic depressives (n = 17) were treated with bilateral ECT under anaesthesia. All patients except two were antidepressant-naive. The auditory P300 event-related potential (ERP) was recorded before and after the ECT course. The latency of P300 in depressives before treatment did not differ from controls, but the amplitude was smaller than in matched controls (n = 15). The P300 amplitude was larger in depressives who had rapid response than in the rest. Rapid responders did not differ from controls on P300 amplitude before treatment. Hence it is suggested that ‘Normal’ P300 predicts rapid therapeutic response to ECT in melancholia.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Electro-convulsive Therapy; Time-course Of Response; P300 Event Related Potential; Melancholia; Prediction Of Ect Response.
ID Code:119431
Deposited On:13 Jun 2021 10:52
Last Modified:13 Jun 2021 10:52

Repository Staff Only: item control page