Heart rate variability as an index of cue reactivity in alcoholics

Rajan, I. ; Naga Venkatesha Murthy, P.J. ; Ramakrishnan, A.G. ; Gangadhar, B.N. ; Janakiramaiah, N. (1998) Heart rate variability as an index of cue reactivity in alcoholics Biological Psychiatry, 43 (7). pp. 544-546. ISSN 0006-3223

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Official URL: http://doi.org/10.1016/S0006-3223(97)00399-5

Related URL: http://dx.doi.org/10.1016/S0006-3223(97)00399-5


Background: Autonomic responses follow exposure to conditioned stimuli such as contextual factors associated with alcohol ingestion. Heart rate variabilty is under autonomic control and may be a measure of such response. Methods: Twenty alcoholics and 23 matched social drinkers (all male) were exposed to a neutral cue and then an alcohol cue in identical settings, during which the electrocardiogram of these subjects was recorded. Time and frequency domain parameters of heart rate variability (HRV) were computed by a blind rater. Results: Coefficient of variation of R-R intervals and absolute powers of HRV spectrum (in frequency bands 0.05-0.15 Hz and 0.01-0.05 Hz) following alcohol cue were significantly higher in alcoholics than social drinkers. The mean heart rate (MHR) failed to reflect this difference. Conclusions: HRV paradigm appears more sensitive than MHR to measure cue reactivity.

Item Type:Article
Source:Copyright of this article belongs to Society of Biological Psychiatry.
Keywords:Heart Rate Variability; Alcohol Dependence; Cue Reactivity.
ID Code:119422
Deposited On:13 Jun 2021 10:12
Last Modified:13 Jun 2021 10:12

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