P300 in family studies of schizophrenia: review and critique

Bharath, S ; Janakiramaiah, N ; Gangadhar, B.N. (2000) P300 in family studies of schizophrenia: review and critique International Journal of Psychophysiology, 38 (1). pp. 43-54. ISSN 0167-8760

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Official URL: http://doi.org/10.1016/S0167-8760(00)00129-X

Related URL: http://dx.doi.org/10.1016/S0167-8760(00)00129-X


The published studies using P300 event-related potential (ERP) as a vulnerability marker in schizophrenia have been summarized and reviewed. Several factors across sibling, offspring, and familial studies appear to contribute to the variegated findings with respect to the utility of P300 as a vulnerability marker for schizophrenia. These include how subject samples are defined in terms of their genetic loading for schizophrenia, sample size, ERP methodology, and the relationship of P300 measures to neuropsychological test outcomes. It was concluded that the P300 holds promise as a vulnerability marker for schizophrenia, if used in conjunction with other neuroimaging and neuropsychological testing methods.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:P300; Schizophrenia; Vulnerability Marker; High-Risk Population.
ID Code:119220
Deposited On:09 Jun 2021 06:32
Last Modified:09 Jun 2021 06:32

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