Heart rate variability during sleep in detoxified alcohol-dependent males: A comparison with healthy controls

Muralidharan, Kesavan ; Benegal, Vivek ; Gangadhar, BangaloreN ; Ganesha, Suhas ; Thirthalli, Jagadisha (2013) Heart rate variability during sleep in detoxified alcohol-dependent males: A comparison with healthy controls Indian Journal of Psychiatry, 55 (2). p. 173. ISSN 0019-5545

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Official URL: http://doi.org/10.4103/0019-5545.111458

Related URL: http://dx.doi.org/10.4103/0019-5545.111458

Abstract

Context: Alcohol dependence can lead to autonomic neuropathy resulting in increased cardiac morbidity and mortality. This has previously been evaluated using heart-rate variability. Aims: We compared sleep heart-rate variability of alcohol-dependent patients with that of healthy controls in this study. Settings and Design: This study was conducted at NIMHANS, Bangalore. A case control study design was adopted. Materials and Methods: Sleep heart-rate variability of 20 male alcohol-dependent inpatients was recorded on the 5 th day after detoxification. Sleep heart-rate variability was also recorded in 18 age- and gender-matched healthy controls. Statistical Analysis: The groups were compared using t-test for continuous variables and Chi-squared test for discrete variables. Results: Both time and frequency domain measures were significantly lower in the patients as compared to the controls, indicating decreased HRV in alcohol-dependent individuals. Conclusions: Decreased HRV in alcohol dependence indicates potential autonomic neuropathy.

Item Type:Article
Source:Copyright of this article belongs to Indian Psychiatric Society.
ID Code:118740
Deposited On:28 May 2021 09:27
Last Modified:28 May 2021 09:27

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