‘Click’ synthesis of cobalt bis(dicarbollide)–cholesterol conjugates

Druzina, Anna A. ; Shmalko, Akim V. ; Andreichuk, Ekaterina P. ; Zhidkova, Olga B. ; Kosenko, Irina D. ; Semioshkin, Andrey ; Sivaev, Igor B. ; Mandal, Swadhin ; Shen, Zheyu ; Bregadze, Vladimir I. (2019) ‘Click’ synthesis of cobalt bis(dicarbollide)–cholesterol conjugates Mendeleev Communications, 29 (6). pp. 628-630. ISSN 09599436

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Official URL: http://doi.org/10.1016/j.mencom.2019.11.007

Related URL: http://dx.doi.org/10.1016/j.mencom.2019.11.007

Abstract

New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using ‘click’ cycloaddition of 3b-(2-azidoethyl) cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.

Item Type:Article
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ID Code:118213
Deposited On:19 May 2021 07:38
Last Modified:19 May 2021 07:38

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