Pratap, Ramendra ; Prakash Kushwaha, Shom ; Goel, Atul ; Ram, Vishnu Ji (2007) An efficient synthesis of (E)-(2-arylpyrazino[1,2-a]pyrimidine-4-ylidene)acetonitriles and cyanomethyl appended pyrimidines Tetrahedron Letters, 48 (4). pp. 549-553. ISSN 0040-4039
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Official URL: http://doi.org/10.1016/j.tetlet.2006.11.136
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.11.136
Abstract
A series of (E)-(2-arylpyrazino[1,2-a]pyrimidine-4-ylidene)acetonitriles 5a–j and aryl/heteroaryl tethered pyrimidin-4-yl acetonitriles 6a–e has been synthesized in excellent yields through base catalyzed ring transformation of suitably functionalized 2H-pyran-2-ones 3 using 2-aminopyrazine 4a and arylamidinium salts 4b, separately.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | 4-Pyrimidinyl acetonitrile; Pyrazino[1,2-a]pyrimidines; 2H-Pyran-2-ones; Ring Transformation. |
| ID Code: | 117924 |
| Deposited On: | 06 May 2021 09:08 |
| Last Modified: | 06 May 2021 09:08 |
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