Tetraazaacenaphthene and tetraazaphenalene derivatives: A new class of hepatoprotectants: Part IV

Ram, Vishnu J. ; Goel, Atul ; Patnaik, G.K. (1995) Tetraazaacenaphthene and tetraazaphenalene derivatives: A new class of hepatoprotectants: Part IV Bioorganic & Medicinal Chemistry Letters, 5 (14). pp. 1541-1544. ISSN 0960-894X

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Official URL: http://doi.org/10.1016/0960-894X(95)00246-P

Related URL: http://dx.doi.org/10.1016/0960-894X(95)00246-P

Abstract

The synthesis and hepatoprotective activity of imidazolidine (3a), hexahydropyrimidine (3b), imidazo[3,2-c]pyrimidine (5), tetraazaacenaphthene (4a-d) and tetraazaphenalene (4e) derivatives are described. Some of the screened compounds have shown a very significant activity. Synthesis and hepatoprotective activity of the compounds 3a,b, 4a-e and 5 are described.

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