Molecular Characterization andIn VitroAntifungal Susceptibility Profile of Schizophyllum commune, an Emerging Basidiomycete in Bronchopulmonary Mycoses

Chowdhary, Anuradha ; Kathuria, Shallu ; Singh, Pradeep Kumar ; Agarwal, Kshitij ; Gaur, Shailendra N. ; Roy, Pradip ; Randhawa, Harbans S. ; Meis, Jacques F. (2013) Molecular Characterization andIn VitroAntifungal Susceptibility Profile of Schizophyllum commune, an Emerging Basidiomycete in Bronchopulmonary Mycoses Antimicrobial Agents and Chemotherapy, 57 (6). pp. 2845-2848. ISSN 0066-4804

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Official URL: http://doi.org/10.1128/AAC.02619-12

Related URL: http://dx.doi.org/10.1128/AAC.02619-12

Abstract

Schizophyllum commune (n = 30) showed lowest geometric mean MICs of isavuconazole (0.19 μg/ml), itraconazole (0.2 μg/ml), voriconazole (0.24 μg/ml), and amphotericin B (0.29 μg/ml) and high geometric mean MICs of fluconazole (19.39 μg/ml) and flucytosine (17.28 μg/ml). Five cases (of 8) of allergic bronchopulmonary mycosis that were treated with itraconazole had no recrudescence after 6 to 24 months of follow-up. One case each of invasive pulmonary mycosis and fungal ball were treated successfully with voriconazole and itraconazole.

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Deposited On:27 Apr 2021 07:34
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