Espinel-Ingroff, A. ; Chowdhary, A. ; Gonzalez, G. M. ; Guinea, J. ; Hagen, F. ; Meis, J. F. ; Thompson, G. R. ; Turnidge, J. (2015) Multicenter Study of Isavuconazole MIC Distributions and Epidemiological Cutoff Values for the Cryptococcus neoformans-Cryptococcus gattii Species Complex Using the CLSI M27-A3 Broth Microdilution Method Antimicrobial Agents and Chemotherapy, 59 (1). pp. 666-668. ISSN 0066-4804
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Official URL: https://aac.asm.org/content/59/1/666
Related URL: http://dx.doi.org/10.1128/AAC.04055-14
Abstract
Epidemiological cutoff values (ECVs) of isavuconazole are not available for Cryptococcus spp. The isavuconazole ECVs based on wild-type (WT) MIC distributions for 438 Cryptococcus neoformans nongenotyped isolates, 870 isolates of genotype VNI, and 406 Cryptococcus gattii isolates from six laboratories and different geographical areas were 0.06, 0.12, and 0.25 μg/ml, respectively. These ECVs may aid in detecting non-WT isolates with reduced susceptibilities to isavuconazole.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Society for Microbiology. |
| ID Code: | 117539 |
| Deposited On: | 26 Apr 2021 11:26 |
| Last Modified: | 26 Apr 2021 11:26 |
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