In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates

Chowdhary, Anuradha ; Hagen, Ferry ; Curfs-Breuker, Ilse ; Madrid, Hugo ; de Hoog, G. Sybren ; Meis, Jacques F. (2015) In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates Antimicrobial Agents and Chemotherapy, 59 (10). pp. 6642-6645. ISSN 0066-4804

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Official URL: http://doi.org/10.1128/AAC.01218-15

Related URL: http://dx.doi.org/10.1128/AAC.01218-15

Abstract

The in vitro susceptibilities of 24 worldwide Exserohilum isolates belonging to 10 species from human and environmental sources were determined for eight antifungal drugs. The strains were characterized by internal transcribed spacer (ITS) sequencing and amplified fragment length polymorphism fingerprinting. Posaconazole had the lowest geometric mean MIC (0.16 μg/ml), followed by micafungin (0.21 μg/ml), amphotericin B (0.24 μg/ml), itraconazole (0.33 μg/ml), voriconazole (0.8 μg/ml), caspofungin (1.05 μg/ml), isavuconazole (1.38 μg/ml), and fluconazole (15.6 μg/ml).

Item Type:Article
Source:Copyright of this article belongs to American Society for Microbiology.
ID Code:117524
Deposited On:26 Apr 2021 10:07
Last Modified:26 Apr 2021 10:07

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