Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon?

Zoran, Tamara ; Sartori, Bettina ; Sappl, Laura ; Aigner, Maria ; Sánchez-Reus, Ferran ; Rezusta, Antonio ; Chowdhary, Anuradha ; Taj-Aldeen, Saad J. ; Arendrup, Maiken C. ; Oliveri, Salvatore ; Kontoyiannis, Dimitrios P. ; Alastruey-Izquierdo, Ana ; Lagrou, Katrien ; Cascio, Giuliana Lo ; Meis, Jacques F. ; Buzina, Walter ; Farina, Claudio ; Drogari-Apiranthitou, Miranda ; Grancini, Anna ; Tortorano, Anna M. ; Willinger, Birgit ; Hamprecht, Axel ; Johnson, Elizabeth ; Klingspor, Lena ; Arsic-Arsenijevic, Valentina ; Cornely, Oliver A. ; Meletiadis, Joseph ; Prammer, Wolfgang ; Tullio, Vivian ; Vehreschild, Jörg-Janne ; Trovato, Laura ; Lewis, Russell E. ; Segal, Esther ; Rath, Peter-Michael ; Hamal, Petr ; Rodriguez-Iglesias, Manuel ; Roilides, Emmanuel ; Arikan-Akdagli, Sevtap ; Chakrabarti, Arunaloke ; Colombo, Arnaldo L. ; Fernández, Mariana S. ; Martin-Gomez, M. Teresa ; Badali, Hamid ; Petrikkos, Georgios ; Klimko, Nikolai ; Heimann, Sebastian M. ; Uzun, Omrum ; Roudbary, Maryam ; de la Fuente, Sonia ; Houbraken, Jos ; Risslegger, Brigitte ; Lass-Flörl, Cornelia ; Lackner, Michaela (2018) Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon? Frontiers in Microbiology, 9 . ISSN 1664-302X

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Official URL: http://doi.org/10.3389/fmicb.2018.00516

Related URL: http://dx.doi.org/10.3389/fmicb.2018.00516

Abstract

Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by members of the section Terrei. The frequency of Aspergillus terreus and related (cryptic) species in clinical specimens, as well as the percentage of azole-resistant strains remains to be studied.

Item Type:Article
Keywords:Cryptic Species; Aspergillus Section Terrei; Susceptibility Profiles, Azoles; Cyp51A Alterations.
ID Code:117400
Deposited On:20 Apr 2021 04:42
Last Modified:20 Apr 2021 04:42

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