A convenient synthetic route to enantiopure N-tosylazetidines from α-amino acids

Ghorai, Manas K. ; Das, Kalpataru ; Kumar, Amit (2007) A convenient synthetic route to enantiopure N-tosylazetidines from α-amino acids Tetrahedron Letters, 48 (14). pp. 2471-2475. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2007.02.033

Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.02.033

Abstract

A general and convenient synthetic route to various chiral 2-substituted- and 2,4-disubstituted-N-tosylazetidines (ee >99%) is described in good overall yields starting from chiral α-amino acids using very simple chemistry.

Item Type:Article
Source:Copyright of this article belongs to Elsevier B.V.
Keywords:Chiral Substituted-N-Tosylazetidine; 2-Cyano-N-Tosylazetidine; α-Amino Acid; β-Amino acid; β-Amino Aldehyde; Chiral Cyanohydrin; Enantiopure.
ID Code:117132
Deposited On:15 Apr 2021 08:10
Last Modified:15 Apr 2021 08:10

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