Enantioselective synthesis of α,β-diamino ester derivatives: memory of chirality in imino-aldol reactions

Ghorai, Manas K. ; Ghosh, Koena ; Yadav, A.K. (2009) Enantioselective synthesis of α,β-diamino ester derivatives: memory of chirality in imino-aldol reactions Tetrahedron Letters, 50 (4). pp. 476-479. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2008.11.050

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.11.050

Abstract

A simple strategy for the synthesis of chiral α,β-diamino ester derivatives in good yields and ee (up to 92%) utilizing the ‘memory of chirality’ concept is reported. This methodology has been extended for the enantioselective synthesis of substituted aziridines with excellent ee (92%).

Item Type:Article
Source:Copyright of this article belongs to Elsevier B.V.
Keywords:Memory of Chirality; Enolate; Imino-aldol; Α,Β-diamino Esters; Aziridine.
ID Code:117125
Deposited On:15 Apr 2021 08:01
Last Modified:15 Apr 2021 08:01

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