Ghorai, Manas K. ; Tiwari, Deo Prakash (2013) Enantioselective Synthesis of 4,5-Dihydropyrroles via Domino Ring-Opening Cyclization (DROC) ofN-Activated Aziridines with Malononitrile The Journal of Organic Chemistry, 78 (6). pp. 2617-2625. ISSN 0022-3263
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Official URL: http://doi.org/10.1021/jo302815m
Related URL: http://dx.doi.org/10.1021/jo302815m
Abstract
An efficient and practical strategy for the synthesis of highly functionalized racemic and non-racemic 4,5-dihydropyrroles via domino ring-opening cyclization (DROC) of activated aziridines with malononitrile in excellent yield and stereoselectivity is described. The reaction serves as a tool for the synthesis of a large variety of substituted 4,5-dihydropyrroles in enantiomerically pure forms.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 117114 |
| Deposited On: | 15 Apr 2021 07:59 |
| Last Modified: | 15 Apr 2021 07:59 |
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