Ghorai, Manas ; Samanta, Sauvik ; Mal, Abhijit ; Halder, Sandipan (2015) Racemization-Free Synthesis of Morpholinone Derivatives from α-Amino Acids Synthesis, 47 (23). pp. 3776-3782. ISSN 0039-7881
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Official URL: http://doi.org/10.1055/s-0035-1560088
Related URL: http://dx.doi.org/10.1055/s-0035-1560088
Abstract
A simple strategy is reported for the synthesis of chiral N-protected morpholinone derivatives by a base (potassium carbonate)-mediated cyclization reaction of N-protected α-amino acids with 1,2-dibromoethane. The morpholinone derivatives are obtained in good yields and in enantiomerically pure forms.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Georg Thieme Verlag KG. |
| Keywords: | Morpholines; Asymmetric Synthesis; Amino Acids; Cyclizations. |
| ID Code: | 117102 |
| Deposited On: | 15 Apr 2021 07:53 |
| Last Modified: | 15 Apr 2021 07:53 |
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