Ring Expansions of Activated Aziridines and Azetidines

Ghorai, Manas K. ; Bhattacharyya, Aditya ; Das, Subhomoy ; Chauhan, Navya (2015) Ring Expansions of Activated Aziridines and Azetidines Topics in Heterocyclic Chemistry, 41 . pp. 49-142. ISSN 1861-9282

Full text not available from this repository.

Official URL: http://doi.org/10.1007/7081_2015_159

Related URL: http://dx.doi.org/10.1007/7081_2015_159


Facile construction of small and normal-sized, or more precisely, four to seven-membered aza-heterocyclic ring systems is always a challenging yet rewarding task for the synthetic organic chemists. Fortunately, activated aziridines and azetidines provide a direct and convenient access to this coveted molecular architectures through several elegant ring-expansion approaches. This chapter presents some of the illustrative and contemporary examples to demonstrate the synthetic diversity and efficiency of the ring-expansion strategies of activated aziridines and azetidines towards a vast array of small to normal-sized aza-heterocyclic moieties.

Item Type:Article
Source:Copyright of this article belongs to Springer Nature Switzerland AG.
Keywords:Activated Azetidines; Activated Aziridines; Domino Ring-opening Cyclization (Droc); Heterocycle; Intramolecular Cyclization; Ring Expansion; Sn2-type Ring Opening.
ID Code:117100
Deposited On:15 Apr 2021 07:53
Last Modified:15 Apr 2021 07:53

Repository Staff Only: item control page