Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis

Swarup, Vivek ; Ghosh, Joydeep ; Ghosh, Soumya ; Saxena, Amit ; Basu, Anirban (2007) Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis Antimicrobial Agents and Chemotherapy, 51 (9). pp. 3367-3370. ISSN 0066-4804

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Official URL: http://doi.org/10.1128/AAC.00041-07

Related URL: http://dx.doi.org/10.1128/AAC.00041-07

Abstract

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

Item Type:Article
Source:Copyright of this article belongs to American Society for Microbiology.
Keywords:Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cinnamates; Depsides; Encephalitis; Japanese.
ID Code:115673
Deposited On:18 Mar 2021 04:41
Last Modified:22 Mar 2021 06:48

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