First synthesis of methyl α-C-D-arabinofuranosyl-(1→5)-α-D-arabinofuranoside: the C-disaccharide segment of motif C of Mycobacterium tuberculosis

Gurjar, Mukund K. ; Nagaprasada, Ravi ; Ramana, C. V. (2002) First synthesis of methyl α-C-D-arabinofuranosyl-(1→5)-α-D-arabinofuranoside: the C-disaccharide segment of motif C of Mycobacterium tuberculosis Tetrahedron Letters, 43 (42). pp. 7577-7579. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(02)01760-4

Abstract

The synthesis of C-analogue of the disaccharide 2 α-araf-(1→5)-araf, present in motif C of the arabino-galactan portion of Mycobacterium tuberculosis, has been described. The critical C-C bond formation reaction to couple both the furanosyl residues has been accomplished through nitro-aldol condensation. The synthesis of C-analogue 2 of the α-araf-(1→5)-araf disaccharide present in motif C of the arabino-galactan portion of Mycobacterium tuberculosis, has been described using the nitro-aldol condensation as the key step.

Item Type:Article
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ID Code:11480
Deposited On:16 Nov 2010 13:54
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