Comparison of echocardiographic acoustic quantification system and radionuclide ventriculography for estimating left ventricular ejection fraction: Validation in patients without regional wall motion abnormalities

Chandra, Subhash ; Bahl, Vinay K. ; Reddy, S. Chandra Bose ; Bhargava, Balram ; Malhotra, Arun ; Wasir, Harbans S. (1997) Comparison of echocardiographic acoustic quantification system and radionuclide ventriculography for estimating left ventricular ejection fraction: Validation in patients without regional wall motion abnormalities American Heart Journal, 133 (3). pp. 359-363. ISSN 0002-8703

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Official URL: https://www.ahjonline.com/article/S0002-8703(97)70...

Related URL: http://dx.doi.org/10.1016/S0002-8703(97)70233-3

Abstract

Echocardiographic automated border detection of blood-endocardium interface is made on the basis of the principle of acoustic quantification. The automated border system is capable of providing on-line left ventricular (LV) cavity area and function. Recently, ABD algorithms have been devised to estimate LV volume on line from a long-axis image, calculated by established area-length method or Simpson's formula. To test the clinical validity of this newly developed echocardiographic method, LV volumes and ejection fraction measured by real-time acoustic quantification were compared with radionuclide ejection fraction in 24 subjects on the same day. Patients were included in the study if ≥75% of their endocardium was visualized with conventional two-dimensional echocardiography. Sixteen (66%) of 24 patients had a technically adequate conventional echocardiogram with a broad range of ventricular dimensions and systolic function. None of the study patients had regional wall motion abnormalities. Echocardiographic measurements were obtained from the LV apical four-chamber, long-axis view. Ejection fraction, determined by the acoustic quantification and by radionuclide ventriculography, showed a strong linear relation ( r = 0.92, standard error of the estimate = 4.4, p < 0.05). However, acoustic quantification overestimated the radionuclide ejection fraction with rather wide limits of agreement (3.8% ± 16.4%; bias ± 2 SD). Thus echocardiographic automated border detection technique is a reasonably accurate method for on-line assessment of LV function.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:114772
Deposited On:04 Jun 2018 04:40
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