Mohapatra, Debendra K. ; Maity, Pradip K. ; Gonnade, Rajesh G. ; Chorghade, Mukund S. ; Gurjar, Mukund K. (2007) Synthesis of new chiral 4,5,6,7-tetrahydro [1,2,3] triazolo [1,5-a] pyrazines from α-amino acid derivatives under mild conditions Synlett, 12 . pp. 1893-1896. ISSN 0936-5214
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Official URL: http://www.thieme-connect.com/ejournals/abstract/s...
Related URL: http://dx.doi.org/10.1055/s-2007-984537
Abstract
A practical and efficient regioselective synthesis of several new chiral 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazines is described from α -amino acid derivatives following intramolecular 'click' reaction as the key step. The method obviates product -purification; to obtain the pure triazole products, only the solvent needs to be evaporated.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers Inc. |
| Keywords: | Pyrazine; 1,2,3-triazole; α-Amino Acid; Click Chemistry; 1,3-dipolar cycloaddition |
| ID Code: | 11457 |
| Deposited On: | 16 Nov 2010 13:56 |
| Last Modified: | 02 Jun 2011 09:41 |
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