Regiospecific benzoylation of electron-deficient N-heterocycles with methylbenzenes via a minisci-type reaction

Ali, Wajid ; Behera, Ahalya ; Guin, Srimanta ; Patel, Bhisma K. (2015) Regiospecific benzoylation of electron-deficient N-heterocycles with methylbenzenes via a minisci-type reaction The Journal of Organic Chemistry, 80 (11). pp. 5625-5632. ISSN 0022-3263

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Official URL: https://pubs.acs.org/doi/abs/10.1021/acs.joc.5b005...

Related URL: http://dx.doi.org/10.1021/acs.joc.5b00501

Abstract

A regioselective cross-dehydrogenative coupling between electron-deficient N-heterocycles (isoquinoline, quinolines, and quinoxalines) and methylbenzenes leading to regiospecific C–aroylation has been accomplished using AlCl3 as the catalyst in the presence of oxidant TBHP. This protocol is a practical alternative to the classical Minisci reaction.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:114037
Deposited On:02 May 2018 04:52
Last Modified:02 May 2018 04:52

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